Victorian government portal for older people, with information about government and community services and programs. Type a minimum of three characters then press UP or DOWN on the keyboard to navigate the autocompleted search results. There are several different types of hormone therapies.
Current or recent past users of hormonal replacement therapy HRT have a higher risk of being diagnosed with breast cancer. Before the link between HRT use and breast cancer risk was established, many postmenopausal women took HRT for many years to ease menopausal symptoms hot flashes, fatigue and to reduce bone loss. Still, many women continue to use HRT to handle bothersome menopausal symptoms.
Some types of breast cancer are affected by hormones in the blood. ER-positive and PR-positive breast cancer cells have receptors proteins that attach to estrogen, which helps them grow. There are different ways to stop estrogen from attaching to these receptors.
Estrogens, a group of female sex hormones, are known human carcinogens. Although these hormones have essential physiological roles in both females and males, they have also been associated with an increased risk of certain cancers. Menopausal hormone therapy with estrogen alone increases the risk of endometrial cancer and is used only in women who have had a hysterectomy. A woman who is thinking about menopausal hormone therapy should discuss the possible risks and benefits with her doctor.
In the Women's Health Initiative, 8, women took combination hormone replacement therapy estrogen and progestin and were followed for an average of 5. The women were evaluated for high risk by the Gail Model and were not found to be at increased risk of developing breast cancer. They had yearly mammograms and breast exams during their follow-up visits.
This is particularly true when the body has too much estrogen and not enough progesterone to counteract it. This situation is called estrogen dominance. Estrogen dominance is a complex situation, the causes of which include:.
Back to Breast cancer in women. The causes of breast cancer aren't fully understood, making it difficult to say why one woman may develop breast cancer and another may not. Some of these you can't do anything about, but there are some you can change.
It is very popular to vilify estrogen these days. The most obvious reason is the result of several sensationalized interpretations of the famous WHI Women's Health Initiative "Prempro" data first out in While the attempt to objectify the effects of post-menopausal hormone replacement therapy is highly admirable, confusion and inappropriate interpretations have resulted in unprecedented fear of "all things estrogen. REALITY: The best data indicates that not only does estrogen not cause breast cancer; estrogen supplementation after menopause might have a slight protective effect.
Find information and resources for current and returning patients. Learn about clinical trials at MD Anderson and search our database for open studies. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services.
Hormone therapy for breast cancer is a treatment for breast cancers that are sensitive to hormones. The most common forms of hormone therapy for breast cancer work by blocking hormones from attaching to receptors on cancer cells or by decreasing the body's production of hormones. Hormone therapy is only used for breast cancers that are found to have receptors for the naturally occurring hormones estrogen or progesterone. Hormone therapy for breast cancer is often used after surgery to reduce the risk that the cancer will return.